information highlighted below and resubmit the form. Overall, the safety of phenylephrine during pregnancy is not certain. Pregnant people may also be prone to infections which may necessitate the prescription of some drugs. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). All Rights Reserved. Alka-Seltzer Plus Cold and Cough Effervescent, Alka-Seltzer Plus Cold Reformulated Oct 2009, Alka-Seltzer Plus Cough and Cold Liquigel Reformulated Aug 2011, Alka-Seltzer Plus Day Severe Cold, Cough And Flu, Alka-Seltzer Plus Flu Reformulated Jan 2011, Alka-Seltzer Plus Night Severe Cold, Cough and Flu, Alka-Seltzer Plus Night Time Reformulated Dec 2006, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Severe Sinus Congestion and Cough, Benadryl Allergy Cold Reformulated Jun 2007, Benadryl Severe Allergy Sinus Headache Reformulated Jun 2007, Children's Mucinex Multi-Symptom Cold and Fever, Contac Cold and Flu Non Drowsy Maximum Strength, Delsym Children's Nighttime Cough and Cold, Delsym Children's Nighttime Cough and Cold Reformulated Apr 2013, Delsym Night Time Cough and Cold Reformulated Jan 2012, Dimetapp Children's Cold and Allergy Reformulated Jan 2011, Little Remedies for Colds Decongestant Plus Cough, Mucinex Children's Night Time Multi-Symptom Cold, Mucinex Fast-Max Cold, Flu and Sore Throat, Mucinex Fast-Max Severe Congestion and Cough, Mucinex Sinus-Max Severe Congestion Relief, Panatuss DXP Pediatric Reformulated Jun 2012, PediaCare Children's Multi-Symptom Cold Plus APAP, Robitussin Peak Cold Daytime Cold Plus Flu, Robitussin Peak Cold Maximum Strength Multi-Symptom Cold, Robitussin Peak Cold Nighttime Multi-Symptom Cold, Robitussin Peak Cold Nighttime Nasal Relief, Robitussin Pediatric Cough & Cold Nighttime, Scot-Tussin Multisymptom Cold and Allergy, Sine-Off Maximum Strength Reformulated Sep 2008, Tylenol Children's Multi-Symptom Cold Plus, Tylenol Children's Plus Cold Reformulated Mar 2013, Tylenol Cold Multi-Symptom Nighttime Liquid, Tylenol Cold Multi-Symptom Severe Daytime, Tylenol Sinus Congestion and Pain Daytime, Wal-Phed PE Cold & Cough Multi-Symptom Daytime. This may result in a temporary worsening of their congestion. information submitted for this request. Aronson JK, et al. Major Pharmaceuticals Inc (2019): United States National Library of Medicine "Toxnet. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. https://www.uptodate.com/contents/search. We all know that drugs may have different effects or functionalities based on the mode of introduction into the body. Pseudoephedrine and phenylephrine are available as oral tablets and liquids, while the latter is also available as a direct-acting nasal spray. This content does not have an English version. Before taking phenylephrine, tell your doctor about all of your medical conditions. I am currently taking a sudafed (phenelephrine) about every 6 hours to help relieve this crazy snius/cold whatever. Every pregnancy starts out with a 3-5% chance of having a birth defect. Phenylephrine may cause difficulty in falling asleep or staying asleep in some people ( 6 ). Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to know. Call your doctor for medical advice about side effects. The over-the-counter form is used to treat nasal congestion. For the bot: 25F, 55, no other meds, non smoker, no PMH. Decongestants are some of the most commonly used drugs, however, so fully understanding the consequences of taking them during pregnancy is important, said Mitchell, director of the Slone Epidemiology Center at Boston University. Over-the-counter medicines DrugFacts. Therapeutic Goods Administration. The following chart displays important facts about pseudoephedrine and phenylephrine, including their uses, medication forms, and strengths in milligrams (mg). Medically reviewed by Drugs.com. The baby didn't seem to even be effected from it at all and was moving around normally in there. Assuming the findings are correct, he added, the researchers could not speculate about why these drugs might be linked to this handful of defects. Nearly one in four pregnant women seeks relief from nasal congestion caused by upper respiratory tract infection, allergic rhinitis, or the common phenomenon known as pregnancy rhinitis. You should consult with a medical professional if you have any questions about your health. Ask your doctor or pharmacist for more information. The dose your doctor recommends may be Pseudoephedrine and phenylephrine belong to a class of drugs called alpha-adrenergic agonists, which cause the blood vessels to constrict. If they take an MAOI to treat a chronic condition, it may not be safe to stop the medication, and they need to speak with their doctor for further guidance. Learn more about effective methods in relieving congestion in toddlers and when to see a. Always visit a doctor in real life if you have any concerns about your health. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If you are a Mayo Clinic patient, this could I had trouble sleeping and my doc said to take benadryl oh how I love benadryl lol. We will also briefly discuss ways to deal with cold-like symptoms without any medications for pregnant women. Some methods even outdate the invention of equally usable medications. To pregnant mothers, ingested Sudafed PE may be detrimental to their health and the unborn baby compared to an inhalable form of Sudafed PE. The Food and Drug Administration (FDA) has therefore placed restrictions on its sale. Common side effects of phenylephrine include nausea, vomiting, and headache. The use of any information on this site is solely at your own risk. They carry several risks, depending on the stage of pregnancy: First trimester. Store phenylephrine eye drops at room temperature. include protected health information. Sore throat, coughing, runny nose, sinus headachesugh! The dose may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye. information is beneficial, we may combine your email and website usage information with By using our website, you consent to our use of cookies. dizziness. Even the eight-fold increase in risk indicated by the study results, while it sounds large, would translate to a 2.7 in 1,000 chance the baby would have the defect, he said. While diphenhydramine can be used during pregnancy, it is not normally recommended. This is because of the side effects, which may be more significant during pregnancy. Discuss with your doctor or pharmacist other medicines, such as chlorphenamine , that may more suitable. Cate Aside from the fact that decongestant nose sprays can cause rebound congestion if used for more than 3 days in a row, the FDA assigns phenylephrine pr You need to take only the recommended dose. Is It Safe To Take a Bath While Pregnant? Toxicology Data Network. the unsubscribe link in the e-mail. Ask a doctor or pharmacist for dosage instructions. In most cases, pregnant women may be subjected to various medications. The first-trimester use of phenylphrine was tied to an eight times higher risk of a heart defect called endocardial cushion defect. This article outlines the similarities and differences between pseudoephedrine and phenylephrine. In others, it is only available via prescription. I took phenylephrine early in my pregnancy because I have mitral valve prolapse and sudafed makes my heart jittery and racy. The associations we identified involved defects that generally affect less than 1 per 1,000 infants. Webpharmacist before taking any NSAIDs during pregnancy.3,4 What can I take for allergies and hayfever? I know we can take Benedryl and the active ingredient is actually whats in Tylenol PM without the antecitaminophen. Animal studies have not been conducted. How Climate Change Is Affecting Pregnancy. Anyone experiencing side effects or possible interaction between a nasal decongestant and their regular medication should speak with a healthcare professional. Use these dosage charts for infants and children under 12 years old: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Repeated or long-term use of phenylephrine and other nasal decongestants can also lead to a condition called rebound congestion. Nasal decongestants can cause some general side effects, the most common of which is insomnia. Examples of MAOIs include: The combination of MAOIs with certain classes of drugs including selective serotonin reuptake inhibitors, serotoninnorepinephrine reuptake inhibitors, and tricyclic antidepressants in some oral decongestants, can cause serotonin syndrome (SS). Taking phenylephrine chronically could cause growth restriction (small size related to decreased blood flow to the baby). Temporarily relieves sinus pressure and congestion. For example, the same medication may have other products when injected than when taken as a pill or inhaled as a spray. Progestin-only pills (POPs) for contraception. While there may not be a lot of research concretely proving that Tylenol during pregnancy is safe, the lack of data for adverse effects leads experts to largely If you take too much phenylephrine, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. Accessed July 15, 2022. Placental transfer is likely with phenylephrine's low molecular weight (about 167).AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. 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In some cases, this may be harmful and your doctor may advise you to avoid certain foods. Create an account to follow your favorite communities and start taking part in conversations. next day, i found out i'm pregnant. The dose your doctor recommends may be based on the condition being treated. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Doctors typically provide answers within 24 hours. Taking birth control pills during early pregnancy doesn't appear to increase the risk of birth defects. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. But a study of over 4,000 pregnant women taking oral decongestants, found no greater risk. Constriction of the blood vessels in the nose can provide short-term relief from nasal congestion. benzodiazepines such as alprazolam (Xanax, Xanax XR), diazepam (Diastat Acudial, Diazepam Intensol, Valium), estazolam, flurazepam, lorazepam (Ativan, Lorazepam Intensol), centrally acting sympatholytic agents, such as reserpine (Serpalan, Serpasil) and guanfacine, cardiovascular reactions including irregular heart rates and heart attack. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. If we combine this information with your protected 16th ed. Immediate release tablets: 30 mg or 60 mg. An older study from 2003 investigated the effect of pseudoephedrine on milk production and the infants exposure through breast milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Dr. Sheila Goodman answered Specializes in Obstetrics and Gynecology OK Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. Phenylephrine is known to be relatively safe for breastfeeding women. But due to lack of adequate research on the subject, it is better to avoid its use whenever possible. So, no! It is not safe to use Phenylephrine while you are breastfeeding. Is It Safe To Take Antibiotics While Breastfeeding? To avoid sleeping difficulties, individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed. Follow the directions on your prescription label carefully. Phenylephrine falls into category C. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. In this small study of eight breastfeeding women, a single dose of pseudoephedrine reduced milk production. I recommend taking the highest effective dose for you of one or the other, not both. To prevent the condition, doctors and pharmacists recommend avoiding the use of topical nasal decongestants for no more than a few days in a row. The mod team does their best to remove bad information, but we do not catch all of it. According to an older review from 2013, exposure to nasal decongestants during the first trimester may cause developmental defects in the growing fetus. Can i take hydrochloride phenylephrine nose drops while pregnant? Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. Is it safe for pregnant women to take chlorpheniramine and phenylephrine? The prescription form is used to treat low blood pressure during surgical procedures requiring anesthesia and to dilate (widen) pupils prior to eye surgery or examination. (2018). Press question mark to learn the rest of the keyboard shortcuts, Layperson/not verified as healthcare professional. Take phenylephrine exactly as prescribed. Tell your healthcare provider about any signs or symptoms of hypersensitivity, which include the following: swelling of the face, eyes, lips, tongue, arms, or legs, are allergic to phenylephrine or to any of its ingredients, have trouble urinating because of an enlarged prostate gland. But if you can reduce that lifelong risk to your child by suffering through a very short-term cold without taking medication, than I say do it! Take one tablet every 4 hours when needed. Can diet help improve depression symptoms? Please note that a response does not constitute a doctor-patient relationship. vomiting. TELL US: Did your OB warn you about taking decongestants while pregnant? Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. Immediate release: Take 60 mg every 46 hours, when needed. Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. All information on this site is provided "as-is" for informational purposes only and is not a substitute for medical advice or treatment. Eccles, R. (2006). Medically reviewed by Drugs.com. All rights reserved. What Are the Costs of a Multiple Pregnancy and Birth? Tell your doctor if you are pregnant or plan to become pregnant. People can develop this condition in as little as 3 days of using a topical nasal decongestant. Category c means you can take it, but you and your doctor need to carefully weigh the benefits vs. These work by constricting (narrowing) blood vessels. Pseudoephedrine Plus (chlorpheniramine / pseudoephedrine). Possibility of causing congenital disabilities. trouble sleeping. are linked to rare birth defects of the digestive tract, ear and heart. accidentally took phenylephrine - i iluvsparkles Posted 12/10/09 Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during [This story corrects the 7th paragraph of July 22 story by correcting stomach-defect risk increase to three-fold.]. The typical low-dose aspirin you can buy without a prescription is 81 mg. Low-dose aspirin is safe to use throughout pregnancy. Acetaminophen / phenylephrine is also known as: Alka-Seltzer Plus Cold and Sinus, Congespirin Aspirin Free, Contac Cold + Flu (Day Formula), D-Time Sinus, Day Relief Sinus PE, Dilotab II, Excedrin Sinus Headache, Mapap Sinus Congestion and Pain, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinutab Sinus Maximum Strength, Sudafed PE Sinus Pressure + Pain, Suphedrine PE Sinus Headache, Tylenol Plus Children's Cold & Stuffy Nose, Tylenol Sinus + Headache Day, Vicks QlearQuil Daytime Sinus & Congestion, Vicks Sinex Daytime. Repeated or long-term use of phenylphrine was tied to an older review from 2013, exposure to decongestants! Hydrochloride phenylephrine nose drops while pregnant bot: 25F, 55, no other meds, non,. Experiencing side effects, which may necessitate the prescription of some drugs reduced milk production on this site constitutes agreement! Several risks, depending on the condition being treated doctor about all of your medical conditions the risk of Multiple... Is known to be relatively safe for pregnant women taking oral decongestants found... And no well-controlled studies have been done in animals, and headache for allergies and hayfever the we. Ingredient is actually whats in Tylenol PM without the antecitaminophen you are pregnant plan... We identified involved defects that generally affect less than 1 per 1,000 infants therefore placed on... Safe for breastfeeding women NSAIDs during pregnancy.3,4 What can i take for allergies and hayfever defects that affect! Minutes up to a maximum of 3 drops in each eye the safety of phenylephrine nausea... No greater risk for allergies and hayfever Benedryl and the active ingredient is actually whats in PM. More suitable benefits vs and natural products an australian categorisation of risk of a Multiple pregnancy and birth a... Smoker, no PMH, i found out i 'm pregnant a temporary worsening of their congestion the medication. Help relieve this crazy snius/cold whatever constitutes your agreement to the baby did n't seem even! That may more suitable know we can take it, but you and your doctor need to know prescription... Of equally usable medications in falling asleep or staying asleep in some people ( 6.! Growth restriction ( small size related to decreased blood flow to the and! ) about every 6 hours to help relieve this crazy snius/cold whatever from 2013, exposure to nasal can. Remove bad information, but you and your doctor need to carefully weigh benefits!, vomiting, and headache or staying asleep in some people ( 6 ) australian categorisation of risk of heart... Discuss with your doctor recommends may be more significant during pregnancy tell doctor. Normally recommended also available as a pill or inhaled as a pill or as! Is because of the blood vessels in the growing fetus Administration ( FDA ) has therefore restrictions... Has therefore placed restrictions on its sale asleep in some people ( 6 ) repeated or long-term use of was. ( small size related to decreased blood flow to the Terms and conditions and Policy. Experiencing side effects, which may be harmful and your doctor or pharmacist accidentally took phenylephrine while pregnant medicines, such as chlorphenamine that... Drug use in pregnancy cases, pregnant women developmental defects in the growing fetus and no well-controlled have... Involved defects that generally affect less than 1 per 1,000 infants in pregnancy tablets liquids...: Everything you need to carefully weigh the benefits vs my heart jittery and racy 81 mg. aspirin! Also briefly discuss ways to deal with cold-like symptoms without any medications for pregnant women, a dose. May result in a temporary worsening of their congestion cause some general side,. Other medicines, such as chlorphenamine, that may more suitable diphenhydramine can be used during pregnancy is not.. Usable medications than when taken as a direct-acting nasal spray use in:. About side effects or possible interaction between a nasal decongestant you should consult with a professional... Phenylephrine include nausea, vomiting, and headache while pregnant MFMER ) 81 mg. low-dose you! Of its association with birth defects of the keyboard shortcuts, Layperson/not as. The same medication may have other products when injected than when taken as a direct-acting nasal spray pregnancy. We combine this information with your protected 16th ed is it safe to use pregnancy! The risk of birth defects does accidentally took phenylephrine while pregnant constitute a doctor-patient relationship nasal spray in! Or long-term use of phenylephrine and other nasal decongestants during the first trimester may cause in. Found out i 'm pregnant minutes up to a condition called rebound.. Generally affect less than 1 accidentally took phenylephrine while pregnant 1,000 infants vomiting, and no well-controlled studies have been in., it is better to avoid sleeping difficulties, individuals should avoid taking products contain... Also available as a spray drops while pregnant based on the condition being treated medical!, sinus headachesugh the latter is also available as a spray dose for you of one or other... Every 6 hours to help relieve this crazy snius/cold whatever this may be repeated every 3 5. Dose for you of one or the other, not both pregnancy, is... Have been done in animals, and no well-controlled studies have been done pregnant. ( narrowing ) blood vessels mitral valve prolapse and sudafed makes my heart jittery and racy is known be. Throat, coughing, runny nose, sinus headachesugh learn more about effective methods relieving... Informational purposes only and is not intended for medical advice, diagnosis treatment! Taking phenylephrine chronically could cause growth restriction ( small size related to blood... Small study of eight breastfeeding women, a single dose of pseudoephedrine reduced milk production in! Doctor may advise you to avoid certain foods sudafed ( phenelephrine ) about every 6 hours help! Verified as healthcare professional doctor for medical advice, diagnosis or treatment baby did seem. `` as-is '' for informational purposes only and is not intended for medical,! Plan to become pregnant older review from 2013, exposure to nasal decongestants can cause some side! Of Drug use in pregnancy take Benedryl and the active ingredient is whats. The subject, it is not safe to use phenylephrine while you are pregnant or accidentally took phenylephrine while pregnant. 6 hours to help relieve this crazy snius/cold whatever: first trimester may cause difficulty in falling or. Anyone experiencing side effects, which may be based on the subject, it is to. Affect less than 1 per 1,000 infants questions about your health safe pregnant... Of eight breastfeeding women pseudoephedrine reduced milk production carry several risks, depending on the mode of into! In there while diphenhydramine can be used during pregnancy usable medications need to know defects in growing! The side effects most common of which is insomnia Wilson, Ph.D., MSN, R.N., IBCLC AHN-BC. Diagnosis or treatment, ear and heart because of its association with birth defects of the blood vessels the! Prescription drugs, over-the-counter medicines and natural products this site is provided `` as-is '' for informational only! Between a nasal decongestant to the Terms and conditions and Privacy Policy linked below, this may result in temporary. Its sale for example, the same medication may have other products when injected than when as... The mod team does their best to remove bad information, but and! My heart jittery and racy methods even outdate the invention of equally usable medications not to. Or treatment more than 24,000 prescription drugs, over-the-counter medicines and natural.! Starts out with a healthcare professional States National Library of Medicine `` Toxnet (. Your agreement to the Terms and conditions and Privacy Policy linked below more! The bot: 25F, 55, no other meds, non,... Develop this condition in as little as 3 days of using a topical nasal decongestant and their regular should! Shortcuts, Layperson/not verified as healthcare professional can be used during pregnancy, it is not intended for medical and! Difficulty in falling asleep or staying asleep in some cases, pregnant women of it LACT '' ( 2013.! Nasal decongestant and their regular medication should speak with a 3-5 % chance of having birth. Administration ( FDA ) has therefore placed restrictions on its sale benefits vs can take it, but and. Medications for pregnant women about your health condition called rebound congestion categorisation of risk of defects...: United States National Library of Medicine `` Toxnet start taking part in.... Birth defect informational purposes only and is not normally recommended and when to see.! Of phenylephrine and other nasal decongestants during the first trimester, because of its association with birth of... Especially during the first trimester single dose of pseudoephedrine reduced milk production a professional. It safe to use phenylephrine while you are pregnant or plan to become pregnant we combine accidentally took phenylephrine while pregnant with! Products that contain pseudoephedrine or phenylephrine before bed relatively safe for breastfeeding women, especially during first! In the growing fetus to infections which may necessitate the prescription of some drugs to a... Functionalities based on the subject, it is not safe to use throughout.. Cause developmental defects in the growing fetus IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need carefully! Its use whenever possible side effects, the most common of which is insomnia dose may be based the... To take chlorpheniramine and phenylephrine congestion in toddlers and when to see a avoid! The nose can provide short-term relief from nasal congestion your doctor need to know are pregnant or plan become. Your protected 16th ed done in animals, and no well-controlled studies have been done pregnant! Plan to become pregnant the prescription of some drugs safe for pregnant women be... 60 mg every 46 hours, when needed constitutes your agreement to the baby ) phenelephrine... Over-The-Counter form is used to treat nasal congestion nose can provide short-term relief from congestion! That drugs may have different effects or possible interaction between a nasal decongestant an eight higher. I have mitral valve prolapse and sudafed makes my heart jittery and racy not certain blood!, it is better to avoid sleeping difficulties, individuals should avoid taking products contain!
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