Available for Android and iOS devices. The benefits of booster vaccination are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time. k [ The AstraZeneca vaccine is made up of a number of ingredients, including an active ingredient called an 'antigen' and several other non-active ingredients called 'excipients.' 0000003715 00000 n How to store COVID-19 Vaccine AstraZeneca 6. This means that a COVID-19 vaccine cannot make you sick with COVID-19. Participants will receive 2 doses of AZD1222; the first dose will be administered on Day 1 and the second dose on Day 29. <]/Prev 553136>> During the first stage (Phase I), the new vaccine is provided to small groups of peoplethe first time the vaccine is tested in humans. 0000000016 00000 n You can help by reporting any side effects you may get. Some cases had a fatal outcome. 0000023338 00000 n Preservatives in this vaccine are disodium edetate dihydrate and ethanol. 2. Signs of an allergic reaction may include itchy skin rash, shortness of breath and swelling of the face or tongue. stream 0000009880 00000 n 0000098749 00000 n There are limited data on the use of COVID-19 Vaccine AstraZeneca in pregnant or breastfeeding women. %PDF-1.3 % This webpage was updated on 16 March 2022 to reflect the latest guidance and ensure consistency of information and formatting. If you get any side effects, talk to your doctor, pharmacist or nurse. You will be told when you need to return for your second injection of COVID-19 Vaccine AstraZeneca. 0000010323 00000 n Browse our homepage for up to date content or request information about a specific topic from our team of scientists. According to the information that AstraZeneca and the University of Oxford presented to the United Kingdom's vaccine regulatory agency, this vaccine contains: The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. . Following widespread use of the vaccine there have been extremely rare reports of blood clots in combination with low level of blood platelets. Younger patients may be more likely to experience anaphylaxis. Oops! COVID-19 Vaccine AstraZeneca is given to adults aged 18 years and older. The AstraZeneca vaccine is not a live virus vaccine, it is therefore biologically and clinically unlikely to pose a risk to the breastfeeding child. Like any vaccine, the COVID-19 vaccines do come with potential side effects. Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. Further to this, SAGE recommends that severe and moderately immunocompromised persons should be offered an additional dose of vaccine. A respiratory syncytial virus vaccine or RSV vaccine is a vaccine which prevents infection by respiratory syncytial virus.As of 2023, no licensed vaccine against RSV exists.. 8 dose multidose vial (4 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. WHO recommends the use of the ChAdOx1-S [recombinant] COVID-19 vaccine in pregnant women only when the benefits of vaccination to the pregnant woman outweigh the potential risks. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. Spills should be disinfected using agents with activity against adenovirus. 3. A new investigational treatment for COVID-19: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. EDTA is not listed as an ingredient in the Johnson &. In countries with ongoing xref 2021 Jan 9;397(10269):72-74. doi: 10.1016/S0140-6736(20)32623-4. COVID-19 Vaccine AstraZeneca contains genetically modified organisms (GMOs). Route of administration Intramuscular injection. COVID-19 AstraZeneca Vaccine EUA Fact Sheet for Recipients URL is not yet ready. %PDF-1.7 The second injection can be given between 4 and 12 weeks after the first injection. As new data become available, WHO will update recommendations accordingly. endobj 0000104331 00000 n 0000001596 00000 n The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. Messenger RNA (mRNA) Nucleoside-modified mRNA encoding the viral spike (S) glycoprotein of SARS-CoV-2. %PDF-1.7 % 57 40 shortness of breath, chest pain, leg swelling, leg pain or persistent abdominal (tummy) pain. Surfactants (also called 'emulsifiers') are excipients that can help make sure ingredients like oil and water stay together during the transportation and storage process. Function. RZ%L ?Gss0~ls"+?H~9~ ~~g5-?K~=2_H This includes any possible side effects not listed in this leaflet. In the meantime, we must maintain and strengthen public health and social measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds, and ensuring good ventilation. WHO does not recommend discontinuing breastfeeding because of vaccination. 0000011249 00000 n 0000093244 00000 n This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. This is the same type of vaccine that flu and the Middle East Respiratory Syndrome vaccines have used for years. After the first dose is withdrawn, the vaccine should be used as soon as practically possible and within 6 hours. Health information in your inbox, every other week. The majority of recipients were White (75.5%), 10.1% were Black and 3.5% were Asian; 55.8% were female and 44.2% male. Cayman Chemical. The first ingredient on the listthe weakened adenovirusis the active ingredient in this vaccine. Results from a large clinical trial in the United States and South America indicate that AstraZeneca's COVID-19 vaccine, AZD1222, is well-tolerated and protects against symptomatic COVID-19 disease, including severe disease or hospitalization. xVN@}W#E{I HTJB+!`)m;:KQyX99se To help pregnant women make this assessment, they should be provided with endstream endobj 76 0 obj <> stream 0000006617 00000 n %PDF-1.7 % 4 to 12 weeks. However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). This product contains genetically modified organisms (GMOs). The manufacturer URL for this document will be provided once that is available. This is not enough to cause any noticeable effects. 0000056130 00000 n The second key step in these reactions is caused by EDTA, a calcium-binding agent and stabilizer that is added to the AstraZeneca vaccine. This publication is available at https://www.gov.uk/government/publications/regulatory-approval-of-covid-19-vaccine-astrazeneca/information-for-uk-recipients-on-covid-19-vaccine-astrazeneca, Regulation 174 Information for UK recipients, COVID-19 Vaccine AstraZeneca solution for injection 0000009792 00000 n a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. A third injection may be given at least 8 weeks after the second injection if advised by your doctor. Pack sizes (not all pack sizes may be marketed): MedImmune UK Ltd Possible side effects 5. 0000107188 00000 n Epub 2020 Dec 8. <>stream Published: 2021-05-07. No data are currently available in individuals with a weakened immune system or who are taking chronic treatment that suppresses or prevents immune responses. endstream endobj 75 0 obj <> stream Very rare cases of capillary leak syndrome (CLS) have been reported following vaccination with COVID-19 Vaccine AstraZeneca. Talk to the healthcare provider if you have questions. %PDF-1.7 % 410 0 obj <>stream In all participants, a T-cell response was induced, peaking by day 14, and maintained two months after injection. It uses a chimpanzee adenovirus to carry spike proteins from the . 5. on AstraZeneca COVID-19 vaccine for reports of very rare side effects. 0000106271 00000 n Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. Company: AstraZeneca 0000082759 00000 n 11 Apr 2021. Other reactions reported in this group include muscle aches (60%), malaise (61%), chills (56%), and feeling feverish (51%). WASHINGTON Workers at a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several weeks ago . Last updated by Judith Stewart, BPharm on Feb 15, 2021.. FDA Approved: No Brand name: AZD1222 Generic name: SARS-CoV-2 vaccine Previous Name: ChAdOx1 nCoV-19 Company: AstraZeneca Treatment for: Prevention of COVID-19 AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. 0000002484 00000 n People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. A court in Belgium . hbbd``b` $HpXAv DL) Your doctor, pharmacist or nurse is responsible for storing this vaccine and disposing of any unused product correctly. Well send you a link to a feedback form. Of those who experienced fever, 18% reported temperatures of at least 38C, and 2% reported temperatures of at least 39C. 0000005745 00000 n endstream endobj 819 0 obj <>/Metadata 27 0 R/Outlines 44 0 R/Pages 815 0 R/StructTreeRoot 48 0 R/Type/Catalog/ViewerPreferences<>>> endobj 820 0 obj <. Getty Images. 0000098057 00000 n % During use it can be stored from 2C to 25C. 0000004648 00000 n 0000005016 00000 n Generic name: SARS-CoV-2 vaccine AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. Some of the information might be out of date or no longer relevant. 0000097788 00000 n Be stored from 2C to 25C several weeks ago second injection if advised by your,. Against adenovirus effectiveness against mild and asymptomatic SARS-CoV-2 infection over time There have extremely! 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